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KMID : 1161420100130010116
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Journal of Medicinal Food
2010 Volume.13 No. 1 p.116 ~ p.122
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Strawberry Consumption Is Associated with Increased Antioxidant Capacity in Serum
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Henning Susanne M.
Seeram Navindra P.
Zhang Yanjun
Li Luyi
Gao Kun
Lee Ru-Po
Wang David C.
Zerlin Alona
Karp Hannah
Thames Gail
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Abstract
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Strawberries are known to contain antioxidants, but the significance of ingesting antioxidant-rich fruits remains to be established. In order to determine whether the consumption of strawberries impacted measures of in vivo antioxidant capacity, frozen strawberries (250?g) were administered daily for 3 weeks to 21 healthy female volunteers. Compliance was confirmed by quantitating pelargonidin-glucuronide, urolithin A-glucuronide, and 2,5-dimethyl-4-hydroxy-3-[2H]furanone-glucuronide in plasma and urine by liquid chromatography?mass spectrometry and antioxidant capacity in serum measured by the increase in lag phase of low-density lipoprotein after copper sulfate exposure, DNA strand breaks in lymphocytes, and activity of phase II enzymes. Among these measures lipid peroxidation lag time increased by 20% (P?
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KEYWORD
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anthocyanin, antioxidant activity, 2,5-dimethyl-4-hydroxy-3-[2H]furanone, glucuronide, human intervention, oxidative DNA damage, phase II enzyme, urolithin A
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